A new perspective article titled Human In Vitro Models of Neuroenergetics and Neurometabolic Disturbances: Current Advances and Clinical Perspectives‘ has now been published in Stem Cells Translational Medicine.
Understanding the mechanism behind CNS energy metabolism and their role on brain function is crucial to answer the relevant questions in human neurological conditions. Establishing a physiologically relevant in vitro models of neuroenergetics requires comprehensive understanding of different cell types processes and interaction, also various metabolic pathways and regulatory mechanisms. The article highlights important keypoints in the development of human in vitro model of neuroenergetics, covering both the biology and technology perspectives.