Our lab is excited to announce our participation in a groundbreaking project, ‘Developing a first-in-class vascularized Gut-Brain-Axis-on-chip platform for accelerating research and drug discovery (GBA-CONNECT)‘. In collaboration with Dr.biol. Artūrs Ābols at the Latvian Biomedical Research and Study Centre (BMC), Cellboxlab, and other esteemed partners, the project will run up to mid-2026.
This initiative, funded by the Eureka Eurostars program, aims to develop a cutting-edge Gut-Brain-Axis (GBA) on-chip platform integrating advanced organ-on-chip technologies, including in vitro blood-brain barriers and co-cultured anaerobic microbiota. Next-generation hardware for automated culturing, monitoring, and analysis will also be investigated to address critical gaps in current drug discovery methods. This platform will provide new insights into drug absorption, blood-brain barrier permeability, and drug toxicity evaluation to enhance our understanding of the Gut-Brain-Axis, with the potential to revolutionise therapeutic development for neurological and mental health conditions.
Stay tuned for more updates on the progress of this exciting research!